![]() The extract showed potent antibacterial activity against all strains tested. indica seeds was done against 61 bacterial strains. Mango was also claimed to have anti malaria effect and was found to display in vitro activity against Plasmodium falciparum. A number of biological activities of mangiferin have been suggested, including anti-diabetic and anti-inflammatory abilities. Mango stem-bark aqueous extract has been reported to possess anti-inflammatory, analgesic and immunoprotective effects. There have been several reports on the pharmacological effects and suitability of medicinal plants as phytotherapies for diseases. Phytoconstituents have been found to inhibit bacteria, fungi, viruses and pests. A wide variety of plant/natural products are used in the treatment of infections. The products are potential new antimicrobial therapy in the ethnopharmacology domain.ĭue to report of increasing developments of drug resistance in human pathogen as well as undesirable side effects of certain antimicrobial agents, it is necessary to search for new agents that are better, cheaper and without side effect for treating infectious diseases especially in developing countries. This could be due to low diffusion rate of mango extract in agarose medium, a thing needed to be further investigated. The inhibition zones produced by mango extract were less than those produced by standard positive control drug. The methanol and ethanol extracts of mango seed showed good inhibitory effects against almost all tested strains. Candida albicans and Aspergilllus niger were both inhibited by the extracts. In most test strains comparable zones of inhibitions were noted for both methanol and ethanol extract. The mean zone of inhibition produced ranged between 5 mm and 18 mm with 18 mm/Mycobacterium smegmatis showed the highest zone of inhibition. Except one organism (Rhodococcus equi), no resistance among the tested strains was shown. In vitro antibacterial activities of methanol and ethanol extracts of mango bulb showed inhibitions to tested organisms with variable inhibition zones. ![]() The extracts were tested against the microorganisms using disc diffusion method at different concentrations: 5 mg/mL, 3.75 mg/mL, 3.125 mg/mL, 2.5 mg/mL, 1.875 mg/mL and 1.25 mg/mL). Mango fruit seed were extracted by Soxhlet using methanol and ethanol as solvents. This present study aimed to investigate the in vitro antimicrobial activities of methanol and ethanol extracts of mango seed against 25 representatives gram positive, gram negative, acid fast bacteria and fungi. It is found in the wild in tropical regions and cultivated varieties have been introduced to other warm regions of the world. is a species of mango in the Anacardiaceae family. Keywords: Antimicrobial Mango Seed Mangifera indica L. 1Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, KSAĢDepartment of Clinical Microbiology and Parasitology, College of Medicine, King Khalid University, Abha, KSAģDepartment of Pharmaceutics, College of Pharmacy, Omdurman Islamic University, Omdurman, SudanĮmail: Septemrevised Octoaccepted October 29, 2012
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